Evolving role of stereotactic body radiation therapy in the management of spine metastases: Defining dose and dose constraints Review
| Authors: | Moraes, F. Y.; Chen, X.; Yan, M.; Spratt, D. E.; Redmond, K.; Jackson, W. C.; Yamada, Y. J. |
| Review Title: | Evolving role of stereotactic body radiation therapy in the management of spine metastases: Defining dose and dose constraints |
| Abstract: | When treating solid tumor spine metastases, stereotactic high-dose-per-fraction radiation, given in a single fraction or in a hypofractionated approach, has proved to be a highly effective and safe therapeutic option for any tumor histology, in the setting of de novo therapy, as salvage treatment of local progression after previous radiation, and in the postoperative setting. There are variations in practice based on the clinical presentation, goals of therapy, as well as institutional preferences. As a biologically potent therapy, a thoughtful and careful attention to detail with patient selection, treatment planning, and delivery is crucial for treatment success. © 2020 Elsevier Inc. |
| Keywords: | treatment response; review; treatment planning; radiation dose; evidence based medicine; dosimetry; radiation dose fractionation; cancer control; stereotactic body radiation therapy; esophagus disease; spine metastasis; spinal cord disease; medical expert; re-irradiation; hypofractionated radiotherapy; human; priority journal; spine sbrt; hypofractionated stereotactic body radiation therapy; reirradiation of spine metastases; spine radiosurgery dose constraints; stereotactic spine radiosurgery |
| Journal Title: | Neurosurgery Clinics of North America |
| Volume: | 31 |
| Issue: | 2 |
| ISSN: | 1042-3680 |
| Publisher: | W.B. Saunders Co-Elsevier Inc. |
| Date Published: | 2020-04-01 |
| Start Page: | 167 |
| End Page: | 189 |
| Language: | English |
| DOI: | 10.1016/j.nec.2019.12.001 |
| PUBMED: | 32147009 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 April 2020 -- Source: Scopus |
