Current and novel mapping substances in gynecologic cancer care Review


Authors: Moukarzel, L. A.; Feinberg, J.; Levy, E. J.; Leitao, M. M. Jr
Review Title: Current and novel mapping substances in gynecologic cancer care
Abstract: Many tracers have been introduced into current medical practice with the purpose of improving lymphatic mapping techniques, anatomic visualization, and organ/tissue perfusion assessment. Among them, three tracers have dominated the field: Indocyanine green, technetium-99m radiocolloid (Tc99 m), and blue dye. Tc99 m and blue dye are used individually or in combination; however, given particular challenges with these tracers, such as the need for a preoperative procedure by nuclear medicine and cost, other options have been sought. Indocyanine green has proven to be a promising alternative for certain procedures, as it is easy to use and has quick uptake. Its use in the management of gynecologic cancers was first described for sentinel lymph node mapping in cervical cancer, and later for endometrial and vulvar cancers. This review provides an in-depth look at these mapping substances, their uses, and the potential for new discoveries. © 2020 IGCS and ESGO.
Keywords: sentinel lymph node; uterine cancer; cervical cancer; operative; surgical procedures; Vulvar and Vaginal Cancer
Journal Title: International Journal of Gynecological Cancer
Volume: 30
Issue: 3
ISSN: 1048-891X
Publisher: Lippincott Williams & Wilkins  
Date Published: 2020-03-01
Start Page: 387
End Page: 393
Language: English
DOI: 10.1136/ijgc-2019-001078
PUBMED: 31953349
PROVIDER: scopus
PMCID: PMC7375198
DOI/URL:
Notes: Review -- Source: Scopus
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  1. Mario Leitao
    575 Leitao