Low-grade serous ovarian cancer: State of the science Review
| Authors: | Slomovitz, B.; Gourley, C.; Carey, M. S.; Malpica, A.; Shih, I. M.; Huntsman, D.; Fader, A. N.; Grisham, R. N.; Schlumbrecht, M.; Sun, C. C.; Ludemann, J.; Cooney, G. A.; Coleman, R.; Sood, A. K.; Mahdi, H.; Wong, K. K.; Covens, A.; O'Malley, D. M.; Lecuru, F.; Cobb, L. P.; Caputo, T. A.; May, T.; Huang, M.; Siemon, J.; Fernández, M. L.; Ray-Coquard, I.; Gershenson, D. M. |
| Review Title: | Low-grade serous ovarian cancer: State of the science |
| Abstract: | In January 2019, a group of basic, translational, and clinical investigators and patient advocates assembled in Miami, Florida, to discuss the current state of the science of low-grade serous carcinoma of the ovary or peritoneum–a rare ovarian cancer subtype that may arise de novo or following a diagnosis of serous borderline tumor. The purpose of the conference was to review current knowledge, discuss ongoing research by established researchers, and frame critical questions or issues for future directions. Following presentations and discussions, the primary objective was to initiate future collaborations, uniform database platforms, laboratory studies, and clinical trials to better understand this disease and to advance clinical care outside the boundaries of single academic institutions. This review summarizes the state of the science in five principal categories: epidemiology and patient outcomes, pathology, translational research, patient care and clinical trials, and patients' perspective. © 2020 Elsevier Inc. |
| Keywords: | cancer chemotherapy; treatment outcome; cancer surgery; clinical feature; pathogenesis; review; microscopy; nonhuman; side effect; cancer diagnosis; ovary cancer; pathology; cancer hormone therapy; cancer genetics; patient care; cancer epidemiology; diagnostic test; epithelial ovarian cancer; patient attitude; translational research; randomized controlled trial (topic); phase 2 clinical trial (topic); phase 3 clinical trial (topic); clinical outcome; cancer prognosis; human; female; priority journal; low-grade serous carcinoma of the ovary; low-grade serous carcinoma of the peritoneum |
| Journal Title: | Gynecologic Oncology |
| Volume: | 156 |
| Issue: | 3 |
| ISSN: | 0090-8258 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2020-03-01 |
| Start Page: | 715 |
| End Page: | 725 |
| Language: | English |
| DOI: | 10.1016/j.ygyno.2019.12.033 |
| PUBMED: | 31969252 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Source: Scopus |
