Artificial intelligence in oncology: Current landscape, challenges, and future directions Review


Authors: Lotter, W.; Hassett, M. J.; Schultz, N.; Kehl, K. L.; Van Allen, E. M.; Cerami, E.
Review Title: Artificial intelligence in oncology: Current landscape, challenges, and future directions
Abstract: Artificial intelligence (AI) in oncology is advancing beyond algorithm development to integration into clinical practice. This review describes the current state of the field, with a specific focus on clinical integration. AI applications are structured according to cancer type and clinical domain, focusing on the four most common cancers and tasks of detection, diagnosis, and treatment. These applications encompass various data modalities, including imaging, genomics, and medical records. We conclude with a summary of existing challenges, evolving solutions, and potential future directions for the field. Significance: AI is increasingly being applied to all aspects of oncology, where several applications are maturing beyond research and development to direct clinical integration. This review summarizes the current state of the field through the lens of clinical translation along the clinical care continuum. Emerging areas are also highlighted, along with common challenges, evolving solutions, and potential future directions for the field. © 2024 American Association for Cancer Research.
Keywords: genetics; review; cancer diagnosis; genetic analysis; neoplasm; neoplasms; colorectal cancer; breast cancer; lung cancer; oncology; cancer therapy; prostate cancer; mammography; artificial intelligence; medical oncology; genomics; imaging; nerve cell network; artificial neural network; landscape; procedures; provocation test; humans; human
Journal Title: Cancer Discovery
Volume: 14
Issue: 5
ISSN: 2159-8274
Publisher: American Association for Cancer Research  
Date Published: 2024-05-01
Start Page: 711
End Page: 726
Language: English
DOI: 10.1158/2159-8290.Cd-23-1199
PUBMED: 38597966
PROVIDER: scopus
PMCID: PMC11131133
DOI/URL:
Notes: Review -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PubMed and PDF -- Source: Scopus
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  1. Nikolaus D Schultz
    486 Schultz