| Abstract: |
Given the unique challenges encountered in the diagnosis and treatment of desmoid tumors and the high rate of tumor recurrence, clinicians have sought alternative therapies which maximize efficacy and minimize patient morbidity. Interventional radiology and interventional oncology offer several minimally invasive, percutaneous image-guided procedures that are well suited to the challenges that desmoid tumors present. Fine needle aspiration and core needle biopsy are routinely used as an alternative to open surgical biopsy to obtain cytological and histological specimens for definitive tissue diagnosis of desmoid tumors. Chemical ablation, radiofrequency ablation, and cryoablation have been used to treat patients with desmoid tumors which have recurred after surgery, radiation, and/or chemotherapy, and as a palliative option for patients with unresectable lesions. In this chapter, the mechanism of action and rationale for use, as well as technical and clinical considerations of each technique will be discussed. © Springer Science+Business Media B.V. 2012. |
