Necrotizing fasciitis associated with malignancy Journal Article


Authors: Chen, L. L.; Tayban, K.; Caravanos, C.; Shaz, D.; Halpern, N. A.
Article Title: Necrotizing fasciitis associated with malignancy
Abstract: Necrotizing fasciitis (NF) is a rare soft-tissue condition with a high mortality rate even with treatment. Diagnosis is challenging due to an absence of specific symptoms at the early stages of clinical presentation. NF is typically associated with traumatic injuries, superficial skin breakdown, and surgical procedures. Diabetes mellitus and immunosuppression also increase the risk of developing NF. NF predominantly occurs in the lower extremities, the peritoneum, and the perineum. Treatments include antimicrobials, supportive care, and surgical source control. It is important for clinicians to recognize the association of spontaneous atraumatic NF caused by Clostridium septicum with malignancy, so they can maintain a high index of suspicion and provide timely interventions to optimize patient outcomes.
Journal Title: Journal of the American Association of Nurse Practitioners
Volume: 32
Issue: 2
ISSN: 2327-6886
Publisher: American Association of Nurse Practitioners  
Date Published: 2020-02-01
Start Page: 109
End Page: 112
Language: English
DOI: 10.1097/jxx.0000000000000251
PUBMED: 31373962
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 2 March 2020 -- Source: Scopus
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MSK Authors
  1. Neil A Halpern
    151 Halpern
  2. Yekaterina D Tayban
    16 Tayban
  3. David Joseph Yehuda Shaz
    7 Shaz
  4. Leon Lin Chen
    52 Chen