Lower extremity lymphedema in patients with gynecologic malignancies Journal Article


Authors: Dessources, K.; Aviki, E.; Leitao, M. M. Jr
Article Title: Lower extremity lymphedema in patients with gynecologic malignancies
Abstract: Lower extremity lymphedema is a chronic, often irreversible condition that affects many patients treated for gynecologic malignancies, with published rates as high as 70% in select populations. It has consistently been shown to affect multiple quality of life metrics. This review focuses on the pathophysiology, incidence, trends, and risk factors associated with lower extremity lymphedema secondary to the treatment of cervical, endometrial, ovarian, and vulvar cancers in the era of sentinel lymph node mapping. We review traditional and contemporary approaches to diagnosis and staging, and discuss new technologies and imaging modalities. Finally, we review the data-based treatment of lower extremity lymphedema and discuss experimental treatments currently being developed. This review highlights the need for more prospective studies and metrics, so that we may better evaluate and serve these patients. © IGCS and ESGO 2020. No commercial re-use. See rights and permissions. Published by BMJ.
Keywords: brachytherapy; uterine cancer; cervical cancer; surgical oncology; Vulvar and Vaginal Cancer
Journal Title: International Journal of Gynecological Cancer
Volume: 30
Issue: 2
ISSN: 1048-891X
Publisher: Lippincott Williams & Wilkins  
Date Published: 2020-02-01
Start Page: 252
End Page: 260
Language: English
DOI: 10.1136/ijgc-2019-001032
PUBMED: 31915136
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 2 March 2020 -- Source: Scopus
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MSK Authors
  1. Mario Leitao
    375 Leitao
  2. Emeline Mariam Aviki
    14 Aviki