Frequency of large intrafractional target motions during spine stereotactic body radiation therapy Journal Article

  


Authors: Wu, J.; Wu, J.; Ballangrud, A.; Mechalakos, J.; Yamada, J.; Lovelock, D. M.
Article Title: Frequency of large intrafractional target motions during spine stereotactic body radiation therapy
Abstract: Spine stereotactic body radiation therapy frequently involves the delivery of high doses to targets in proximity to the spinal cord; thus, the radiation must be delivered with great spatial accuracy. Monitoring for large shifts in target and cord position that might occur during dose delivery is a challenge for clinics equipped with a conventional C-arm Linac. Treatment must be halted, then imaging and registration must be done to determine whether a significant shift has occurred. In this retrospective study of 1019 spine SBRT treatments, we investigated the number of target shifts >2 mm in any direction that occurred in carefully immobilized patients. Orthogonal kV images were acquired 3 to 5 times during each session using in an in-room imaging system. Although the likelihood of large intrafractional shifts was found to be very low, they did occur in 6 treatment sessions. Intrafractional monitoring was found to be an important safety component of treatment delivery. © 2019 American Society for Radiation Oncology
Keywords: major clinical study; treatment planning; retrospective study; spine; stereotactic body radiation therapy; cone beam computed tomography; planning target volume; hypofractionated radiotherapy; human; priority journal; article
Journal Title: Practical Radiation Oncology
Volume: 10
Issue: 1
ISSN: 1879-8519
Publisher: Elsevier Inc.  
Date Published: 2020-01-01
Start Page: e45
End Page: e49
Language: English
DOI: 10.1016/j.prro.2019.08.006
PUBMED: 31446148
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85072526662&doi=10.1016%2fj.prro.2019.08.006&partnerID=40&md5=a538a940fcc030dcaf31ca4d176c27c8
Notes: Source: Scopus
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MSK Authors
  1. Yoshiya Yamada
    479 Yamada
  2. Ase M Ballangrud-Popovic
    103 Ballangrud-Popovic
  3. James G Mechalakos
    164 Mechalakos
  4. Dale M Lovelock
    183 Lovelock
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