Ocular melanoma: Total dose and dose rate effects with Co-60 plaque therapy Journal Article


Authors: Beitler, J. J.; McCormick, B.; Ellsworth, R. M.; Abramson, D. H.; Anderson, L. L.; Loffredo, C.
Article Title: Ocular melanoma: Total dose and dose rate effects with Co-60 plaque therapy
Abstract: From 1968 to 1987, 123 consecutive patients with nonmetastatic choroidal melanoma were treated with cobalt-60 plaques. One hundred sixteen patients were followed up for a mean of 3.8 years. Twenty patients had local failure, and 14 patients had distant failure. Complications included 32 cataracts, and seven enucleations were required. Local recurrence did not correlate with tumor height, tumor volume, dose, or dose rate. Increased volume (P = .004) and height (P = .01) correlated with increased rates of distant mé tastases. Dose adjusted for volume did not correlate with the rate of metastases.
Keywords: retrospective studies; follow-up studies; melanoma; neoplasm recurrence, local; radiotherapy dosage; brachytherapy; cataract; choroid melanoma; choroid neoplasms; radioisotope; cobalt radioisotopes; cobalt therapy; human; male; female; priority journal; article; eye, neoplasms, 224.371; eye, therapeutic radiology, 224.1299; melanoma, 224.371
Journal Title: Radiology
Volume: 176
Issue: 1
ISSN: 0033-8419
Publisher: Radiological Society of North America, Inc.  
Date Published: 1990-07-01
Start Page: 275
End Page: 278
Language: English
DOI: 10.1148/radiology.176.1.2353101
PUBMED: 2353101
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 27 January 2020 -- Source: Scopus
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  1. Beryl McCormick
    371 McCormick