Overview of systemic treatment of bladder cancer and results with M-VAC therapy Journal Article
| Author: | Yagoda, A. |
| Article Title: | Overview of systemic treatment of bladder cancer and results with M-VAC therapy |
| Abstract: | Cytotoxic chemotherapy is playing an increasingly important role for advanced disease, and is being properly evaluated in prospective trials as neoadjuvant therapy. There has been no major undertaking to examine adjuvant treatment, and hopefully randomized studies will be started in the future. There is sparse data concerning the effectiveness of immunological agents for treatment of this tumor, and phase II efficacy studies are needed. Future studies will need to define more accurately the poor-risk group in whom new agents or regimens using a more intensive schedule, perhaps with G-CSF, can be explored as initial therapy. |
| Keywords: | survival rate; clinical trial; mortality; review; cisplatin; doxorubicin; multimodality cancer therapy; antineoplastic agents; united states; combined modality therapy; methotrexate; antineoplastic agent; prospective study; prospective studies; randomized controlled trial; antineoplastic combined chemotherapy protocols; drug screening; bladder tumor; urinary bladder neoplasms; vinblastine; randomized controlled trials; drug evaluation; m vac protocol; m-vac protocol; humans; human |
| Journal Title: | Progress in Clinical and Biological Research |
| Volume: | 350 |
| ISSN: | 0361-7742 |
| Publisher: | John Wiley & Sons, Inc. |
| Date Published: | 1990-01-01 |
| Start Page: | 87 |
| End Page: | 99 |
| Language: | English |
| PUBMED: | 2201047 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 27 January 2020 -- Source: Scopus |