(125)iodine reimplantation for locally progressive prostatic carcinoma Journal Article

  


Authors: Wallner, K. E.; Nori, D.; Morse, M. J.; Sogani, P. C.; Whitmore, W. F.; Fuks, Z.
Article Title: (125)iodine reimplantation for locally progressive prostatic carcinoma
Abstract: We treated 13 patients with a second 125iodine implant for local recurrence of prostatic carcinoma. All patients had biopsy proved palpable recurrence without evidence of distant metastases. Full doses of irradiation were used (median matched peripheral dose 170 Gy.). Six patients had complete regression of palpable recurrence, 2 had partial regression, 2 had no apparent response and 3 were unevaluable for local response. Actuarial freedom from local disease progression at 5 years was 51%. Despite a relatively high rate of local disease control the actuarial rate of distant metastases reached 100% at 6 years after reimplantation. There were 2 severe rectal complications and 4 instances of mild to moderate urinary incontinence among the 13 patients. Local regression of recurrent prostatic carcinoma may be achieved with 125iodine reimplantation but most patients still had distant metastases.
Keywords: clinical article; cancer growth; radiation dose; recurrent cancer; follow up; methodology; follow-up studies; neoplasm recurrence, local; radiotherapy dosage; radiotherapy; biopsy; time; time factors; prostatic neoplasms; iodine 125; radioactive iodine; iodine radioisotopes; urine incontinence; tumor recurrence; prostate tumor; carcinoma; brachytherapy; prostate carcinoma; human; male; priority journal; article
Journal Title: Journal of Urology
Volume: 144
Issue: 3
ISSN: 0022-5347
Publisher: Elsevier Science, Inc.  
Date Published: 1990-09-01
Start Page: 704
End Page: 706
Language: English
DOI: 10.1016/s0022-5347(17)39560-5
PUBMED: 2388332
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025193074&doi=10.1016%2fS0022-5347%2817%2939560-5&partnerID=40&md5=c085e522637b044522a1c19d700218c5
Notes: Article -- Export Date: 27 January 2020 -- Source: Scopus
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MSK Authors
  1. Zvi Fuks
    427 Fuks
  2. Pramod C Sogani
    75 Sogani
  3. Willet F. Whitmore Jr
    139 Whitmore
  4. Kent E. Wallner
    48 Wallner
  5. Dattatreyudu Nori
    38 Nori
  6. Michael J. Morse
    40 Morse
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