Intravenous glycerol infusions: Effect on free fatty acid metabolism Journal Article

  

Authors:	Pesola, G. R.; Sauerwein, H. P.; Vydelingum, N. A.; Carlon, G.; Brennan, M. F.
Article Title:	Intravenous glycerol infusions: Effect on free fatty acid metabolism
Abstract:	The plasma-free fatty acid response to intravenous glycerol infused at 250 and 500 mumol/min was determined in five normal volunteers in the postabsorptive state. There was a drop in free fatty acid concentration in all five subjects (one-way ANOVA, p less than 0.01) after the glycerol infusion with no change in insulin concentration compared to the post-absorptive state. These results suggest that intravenous glycerol infusions decrease free fatty acid concentrations in the post-absorptive state by an insulin-independent mechanism. When pharmacologic nonisotopic glycerol infusions are used to determined lipolytic rate, simultaneous measurement of free fatty acid concentrations should be interpreted with caution. © 1990, SAGE Publications. All rights reserved.
Keywords:	adult; insulin; infusions, intravenous; infusion; intravenous drug administration; normal human; human experiment; glycerol; catheterization, central venous; fatty acid metabolism; fatty acids, nonesterified; human; male; priority journal; article; support, non-u.s. gov't; support, u.s. gov't, p.h.s.
Journal Title:	Journal of Parenteral and Enteral Nutrition
Volume:	14
Issue:	2
ISSN:	0148-6071
Publisher:	Sage Publications
Date Published:	1990-03-01
Start Page:	162
End Page:	164
Language:	English
DOI:	10.1177/0148607190014002162
PUBMED:	2191154
PROVIDER:	scopus
DOI/URL:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025265166&doi=10.1177%2f0148607190014002162&partnerID=40&md5=cccad8615961512d4074f6d17106a291
Notes:	Article -- Export Date: 27 January 2020 -- Source: Scopus

https://synapse.mskcc.org/synapse/works/has_related_data_chk/159469