Serologic analysis of human cancer Journal Article
| Authors: | Oettgen, H. F.; Rettig, W. J.; Lloyd, K. O.; Old, L. J. |
| Article Title: | Serologic analysis of human cancer |
| Abstract: | The use of serologic probes in the analysis of cancer antigens and their contribution to the long-disputed issues of cancer-specific antigens and host defenses against cancer are discussed. Several powerful new techniques have been introduced during the past 20 to 30 years, among them hybridoma technology, human B-cell transformation by Epstein-Barr virus, and the cloning of immunoglobulin genes from individual B cells to provide direct access to cataloguing the B-cell repertoire, all of which have allowed serologic analysis to remain one of the most powerful ways to probe structural changes associated with malignant transformation. |
| Keywords: | review; nonhuman; chromosome; mouse; tumor antigen; monoclonal antibody; serology; cancer immunology; human |
| Journal Title: | Immunology and Allergy Clinics of North America |
| Volume: | 10 |
| Issue: | 4 |
| ISSN: | 0889-8561 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1990-11-01 |
| Start Page: | 607 |
| End Page: | 637 |
| Language: | English |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Source: Scopus |
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