Changes in the spectrum of organisms causing bacteremia and fungemia in immunocompromised patients due to venous access devices Journal Article
| Authors: | Kiehn, T. E.; Armstrong, D. |
| Article Title: | Changes in the spectrum of organisms causing bacteremia and fungemia in immunocompromised patients due to venous access devices |
| Abstract: | A significant increase in the use of vascular access devices has changed the spectrum of organisms causing bacteremia and fungemia at Memorial Sloan-Kettering Cancer Center. This paper documents the 1988 laboratory experience with bacteremia and fungemia and contrasts some of that data with information obtained in 1984. In 1988, 439 tunnelled-catheters and 355 ports were inserted in patients; 2,778 organisms were subsequently recovered from 933 episodes of bacteremia and fungemia. Fifty-percent of the episodes of bacteremia and fungemia were vascular access device-related. Compared to 1984, the relative incidence of bacteremia due to gram-positive organisms increased from 33 to 43 %, polymicrobic cultures increased from 24 to 27 %, and the number of organisms with colony counts greater than 100 cfu/ml increased from 24 to 44 %. In 1988, device-related sepsis was often caused by Acinetobacter spp., Bacillus spp., Corynebacterium spp., pseudomonads other than Pseudomonas aeruginosa, and coagulase-negative staphylococci. Infection was also caused by species of flavobacteria, Micrococcus, and Rhodotorula. Efforts required for identification of many of the newer pathogens have escalated material and personnel costs. © 1990 Friedr. Vieweg & Sohn Verlagsgesellschaft mbH. |
| Keywords: | adult; controlled study; major clinical study; comparative study; quantitative assay; immune tolerance; bacteremia; yeast; immune deficiency; catheters, indwelling; septicemia; blood culture; gram positive bacterium; mycoses; gram negative bacterium; colony count, microbial; intravascular catheter; fungemia; human; priority journal; article; anaerobic bacterium |
| Journal Title: | European Journal of Clinical Microbiology and Infectious Diseases |
| Volume: | 9 |
| Issue: | 12 |
| ISSN: | 0934-9723 |
| Publisher: | Springer |
| Date Published: | 1990-12-01 |
| Start Page: | 869 |
| End Page: | 872 |
| Language: | English |
| DOI: | 10.1007/bf01967501 |
| PUBMED: | 2073897 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Source: Scopus |
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