A prospective analysis of vascular access device-related infections in children Conference Paper
| Authors: | La Quaglia, M. P.; Lucas, A.; Thaler, H. T.; Friedlander-Klar, H.; Exelby, P. R.; Groeger, J. S. |
| Title: | A prospective analysis of vascular access device-related infections in children |
| Conference Title: | 38th International Congress of the British Association of Paediatric Surgeons |
| Abstract: | To identify significant predictors of device-related infections, we performed a prospective, nonrandomized analysis of our experience with vascular access devices over a 2-year period in a pediatric oncology population. Variables analyzed included: (1) age at placement, (2) sex, (3) underlying disease, (4) type of device used (catheter v port), and (5) total white blood cell count at placement. Quantitative microbiologic criteria were used for diagnosis of bacteremia while clinical and microbiologic criteria were used in diagnosis of tunnel/port/site infections. During the study period a total of 351 devices, comprising 78, 159 days in situ, were placed and data for univariate and multivariate analysis were available on 271 (77%). The mean age at placement was 7.2 ± 4.7 years for catheters and 9.5 ± 4.8 years for implantable devices (P ≤ .01). Significant predictors of device-related infections in univariate analysis were type of device (P ≤ .0001) and age (P ≤ .002). External catheters and age ≤ 7 years were associated with increased risk of infection. Underlying disease had a marginal effect on the infection rate (P = .08). In multivariate analysis, device type (P ≤ .0001) and age (P ≤ .002) continued to affect infections, whereas underlying disease demonstrated only a borderline effect (P = .14). We conclude that device type and age significantly affect the rate of device-related infections. These data support increased use of implantable devices in pediatric oncology patients. © 1992. |
| Keywords: | adolescent; child; implant; major clinical study; conference paper; prospective studies; infection; risk factors; age; statistical analysis; device; multivariate analysis; bacteremia; leukocyte count; children; infection risk; catheters, indwelling; sex; infectious complication; catheter; gram-negative bacterial infections; infection rate; infections; vascular access; human; male; female; priority journal |
| Journal Title | Journal of Pediatric Surgery |
| Volume: | 27 |
| Issue: | 7 |
| Conference Dates: | 1991 Jul 24-26 |
| Conference Location: | Budapest, Hungary |
| ISBN: | 0022-3468 |
| Publisher: | W.B. Saunders Co-Elsevier Inc. |
| Date Published: | 1992-07-01 |
| Start Page: | 840 |
| End Page: | 842 |
| Language: | English |
| DOI: | 10.1016/0022-3468(92)90379-l |
| PUBMED: | 1640329 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Source: Scopus |
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411La Quaglia -
91Groeger -
245Thaler -
30Exelby
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