In vitro activity of the new semi-synthetic polypeptide cilofungin (LY121019) against Aspergillus and Candida species Journal Article
| Authors: | Huang, A.; Edwards, F.; Bernard, E. M.; Armstrong, D.; Schmitt, H. J. |
| Article Title: | In vitro activity of the new semi-synthetic polypeptide cilofungin (LY121019) against Aspergillus and Candida species |
| Abstract: | The in vitro activity of cilofungin (LY121019), a new semi-synthetic antifungal agent was evaluated. Potent activity was seen against Candida albicans and Candida tropicalis, with almost identical MIC and MFC results, whereas no activity was seen against any isolates of Candida parapsilosis or three Aspergillus spp. However, MICs were dependent on medium and test conditions chosen. It is concluded that cilofungin has good activity against some medically important yeasts in vitro, and that its in vitro activity depends on the method used. © 1990 Friedr. Vieweg & Sohn Verlagsgesellschaft mbH. |
| Keywords: | comparative study; culture medium; in vitro study; peptides; aspergillus; fungus; antifungal activity; antimicrobial activity; candida; minimum inhibitory concentration; fungicidal activity; human; priority journal; article; cilofungin |
| Journal Title: | European Journal of Clinical Microbiology and Infectious Diseases |
| Volume: | 9 |
| Issue: | 9 |
| ISSN: | 0934-9723 |
| Publisher: | Springer |
| Date Published: | 1990-09-01 |
| Start Page: | 697 |
| End Page: | 699 |
| Language: | English |
| DOI: | 10.1007/bf01964276 |
| PUBMED: | 2226501 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work