Clinical and genetic features of human germ cell cancer Journal Article


Authors: Dmitrovsky, E.; Bosl, G. J.; Chaganti, R. S. K.
Article Title: Clinical and genetic features of human germ cell cancer
Abstract: The majority of patients with disseminated germ cell cancer can be cured. However, subsets of these patients are either refractory to initial treatment or relapse after treatment. The management of these different clinical groups is reviewed. An enhanced understanding of the basic biological features of germ cell cancer may well lead to improvements in the management of this disease. Recent advances in the biological and genetic aspects of germ cell cancer which are pertinent to the behaviour of this malignancy are summarized.
Keywords: review; cell transformation, neoplastic; testicular neoplasms; neoplasms, germ cell and embryonal; germ cell tumor; chromosome 12p; differentiation; isochromosome; human; male; female; priority journal; support, non-u.s. gov't; support, u.s. gov't, p.h.s.; human germ cell cancer; human teratocarcinoma isochromosome 12p; tumour differentiation; keratocarcinoma
Journal Title: Cancer Surveys
Volume: 9
Issue: 2
ISSN: 0261-2429
Publisher: Cold Spring Harbor Laboratory Press  
Date Published: 1990-01-01
Start Page: 369
End Page: 386
Language: English
PUBMED: 1964627
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 27 January 2020 -- Source: Scopus
Citation Impact
MSK Authors
  1. Raju S K Chaganti
    391 Chaganti
  2. George Bosl
    430 Bosl
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