Radioimmunotherapy in experimental animal models: Principles derived from models Conference Paper
| Authors: | Scheinberg, D. A.; Strand, M. |
| Title: | Radioimmunotherapy in experimental animal models: Principles derived from models |
| Conference Title: | 2nd Conference on Radioimmunodetection and Radioimmunotherapy of Cancer |
| Abstract: | Experimental animal models have made it possible to study some of the biological, biochemical, and pharmacological parameters involved in the use of radiolabeled monoclonal antibody for therapy and detection. Although such models are less appropriate for studies of dosimetry and the host's immune response to the monoclonal antibody, some general principles have been derived from the various model systems that have largely held true in studies in patients. Some of the points learned from experimental animal models will be illustrated in this paper. |
| Keywords: | nonhuman; conference paper; cancer radiotherapy; animal; animal model; monoclonal antibody; antibodies, monoclonal; neoplasms, experimental; radioisotope; radioimmunotherapy; radioisotopes; human; priority journal; support, non-u.s. gov't; support, u.s. gov't, p.h.s. |
| Journal Title | Cancer Research |
| Volume: | 50 |
| Issue: | 3 Suppl. |
| Conference Dates: | 1988 Sep 8-10 |
| Conference Location: | Princeton, NJ |
| ISBN: | 0008-5472 |
| Publisher: | American Association for Cancer Research |
| Date Published: | 1990-02-01 |
| Start Page: | 962s |
| End Page: | 963s |
| Language: | English |
| PUBMED: | 2297749 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Conference Paper -- Export Date: 27 January 2020 -- Source: Scopus |
