Axillary lymphadenectomy: A prospective, randomized trial of 13 factors influencing drainage, including early or delayed arm mobilization Journal Article


Authors: Petrek, J. A.; Peters, M. M.; Nori, S.; Knauer, C.; Kinne, D. W.; Rogatko, A.
Article Title: Axillary lymphadenectomy: A prospective, randomized trial of 13 factors influencing drainage, including early or delayed arm mobilization
Abstract: • Greater amount and duration of postoperative wound drainage after lymphadenectomy impede healing. We evaluated the influence of early vs delayed initiation of shoulder mobilization on postoperative drainage. Fifty-seven women with clinical stage I or II breast cancer were randomized to either early (postoperative day 2) or delayed (postoperative day 5) shoulder motion. Early vs delayed time of exercise initiation had no effect on total amount or duration of drainage, either as an inpatient or outpatient. The two groups were determined to be homogeneous as to age, breast size, weight, height, obesity, previous biopsy, excision of pectoralis minor, excision of thoracodorsal complex, level of axillary dissection, total number of lymph nodes, number of positive lymph nodes, lymphatic vessel invasion (with negative lymph nodes), and whether the dominant hand was on the side operated on. The two factors predicting greater drainage were large numbers of positive lymph nodes and no previous surgical biopsy (as in one-step procedure). © 1990, American Medical Association. All rights reserved.
Keywords: adult; major clinical study; conference paper; comparative study; combined modality therapy; neoplasm staging; lymph node excision; prospective studies; lymphadenectomy; breast cancer; exercise; breast neoplasms; time factors; age; randomized controlled trials; axilla; drainage; middle age; exercise therapy; arm; human; female; priority journal; early ambulation
Journal Title: Archives of Surgery
Volume: 125
Issue: 3
ISSN: 0004-0010
Publisher: American Medical Association  
Date Published: 1990-03-01
Start Page: 378
End Page: 382
Language: English
DOI: 10.1001/archsurg.1990.01410150100018
PUBMED: 2407228
PROVIDER: scopus
DOI/URL:
Notes: Article -- Source: Scopus
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  1. Jeanne Ann Petrek
    91 Petrek
  2. Margaret M Peters
    5 Peters
  3. David Kinne
    64 Kinne
  4. Andre Rogatko
    23 Rogatko