Awareness and general anaesthesia Conference Paper


Authors: Desiderio, D. P.; Thorne, A. C.
Title: Awareness and general anaesthesia
Conference Title: Midazolam and Flumazenil: The Agonist-Antagonist Concept for Sedation and Anesthesia
Abstract: A state exists after the induction of anaesthesia in which patients may be aware of their surroundings yet unable to communicate. This problem of awareness and recall during general anaesthesia is a recent one in the relatively short history of anaesthesia. Prior to the introduction of muscle relaxants in 1942 by Griffith and Johnson, it was felt that “light anaesthesia” would be signified by violent movements. Today, the concepts of anaesthetic depth, awareness, and recall have become more complicated with the addition of numerous newer, shorter‐acting, intravenous anaesthetic agents with varying effects on the conscious state. Several methods have been described to detect awareness. None has yet been found to be totally reliable and numerous reports of awareness can be found in the literature. Light inhalation and total intravenous anaesthesia have been blamed for the majority of these case reports. However, awareness during total intravenous anaesthesia is avoidable with the proper use of a combination of a hypnotic and an analgesic such as midazolam and alfentanil for general anaesthesia. © 1990 Acta Anaesthesiologica Scandinavica Fonden
Keywords: postoperative period; conference paper; midazolam; drug effect; psychological aspect; general anesthesia; anesthesia, general; cognition; memory; awareness; infusions, intravenous; electroencephalogram; hemodynamics; intravenous drug administration; electroencephalography; vecuronium; alfentanil; human; female; article; depth of anesthesia; total intravenous anesthesia
Journal Title Acta Anaesthesiologica Scandinavica
Volume: 34
Issue: Suppl. 92
Conference Dates: 1989 Apr
Conference Location: Sardinia, Italy
ISBN: 0001-5172
Publisher: Acta Anaesthesiologica Scandinavica Fonden  
Date Published: 1990-06-01
Start Page: 48
End Page: 50
Language: English
DOI: 10.1111/j.1399-6576.1990.tb03183.x
PUBMED: 2327227
PROVIDER: scopus
DOI/URL:
Notes: Article -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Alisa C Thorne
    16 Thorne