Novel imaging techniques of rectal cancer: What do radiomics and radiogenomics have to offer? A literature review Review

   

Authors:	Horvat, N.; Bates, D. D. B.; Petkovska, I.
Review Title:	Novel imaging techniques of rectal cancer: What do radiomics and radiogenomics have to offer? A literature review
Abstract:	Introduction: As computational capabilities have advanced, radiologists and their collaborators have looked for novel ways to analyze diagnostic images. This has resulted in the development of radiomics and radiogenomics as new fields in medical imaging. Radiomics and radiogenomics may change the practice of medicine, particularly for patients with colorectal cancer. Radiomics corresponds to the extraction and analysis of numerous quantitative imaging features from conventional imaging modalities in correlation with several endpoints, including the prediction of pathology, genomics, therapeutic response, and clinical outcome. In radiogenomics, qualitative and/or quantitative imaging features are extracted and correlated with genetic profiles of the imaged tissue. Thus far, several studies have evaluated the use of radiomics and radiogenomics in patients with colorectal cancer; however, there are challenges to be overcome before its routine implementation including challenges related to sample size, model design and interpretability, and the lack of robust multicenter validation set. Material and methods: In this article, we will review the concepts of radiomics and radiogenomics and their potential applications in rectal cancer. Conclusion: Radiologists should be aware of the basic concepts, benefits, pitfalls, and limitations of new radiomic and radiogenomics techniques to achieve a balanced interpretation of the results. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.
Keywords:	positron emission tomography; magnetic resonance imaging; rectal neoplasms; computed tomography; radiogenomics; radiomics
Journal Title:	Abdominal Radiology
Volume:	44
Issue:	11
ISSN:	2366-004X
Publisher:	Springer
Date Published:	2019-11-01
Start Page:	3764
End Page:	3774
Language:	English
DOI:	10.1007/s00261-019-02042-y
PUBMED:	31055615
PROVIDER:	scopus
PMCID:	PMC6824982
DOI/URL:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065337907&doi=10.1007%2fs00261-019-02042-y&partnerID=40&md5=9364e49944e383068168566d65c73580
Notes:	Review -- Export Date: 2 December 2019 -- Source: Scopus

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