Mucinous rectal cancer: Concepts and imaging challenges Review
| Authors: | Horvat, N.; Hope, T. A.; Pickhardt, P. J.; Petkovska, I. |
| Review Title: | Mucinous rectal cancer: Concepts and imaging challenges |
| Abstract: | Rectal adenocarcinoma with mucinous components is an uncommon type of rectal cancer with two distinct histologic subtypes: mucinous adenocarcinoma and signet-ring cell carcinoma. Mucin can also be identified as pattern of response after neoadjuvant treatment. On imaging modalities, mucin typically demonstrates high signal intensity on T2-weighted images, low attenuation on computed tomography, and may be negative on 18-fluorodeoxyglucose positron emission tomography. After neoadjuvant CRT, cellular and acellular mucin share similar imaging features, and differentiating them is currently the main challenge faced by radiologists. Radiologists should be aware of pros, cons, and limitations of each imaging modality in the primary staging and restaging to avoid misinterpretation of the radiological findings. © 2019, Springer Science+Business Media, LLC, part of Springer Nature. |
| Keywords: | treatment response; neoadjuvant therapy; cancer staging; nuclear magnetic resonance imaging; positron emission tomography; magnetic resonance imaging; antineoplastic agent; computer assisted tomography; diagnostic imaging; chronic disease; fluorodeoxyglucose f 18; rectum carcinoma; colloid carcinoma; rectal neoplasms; signet ring carcinoma; chemoradiotherapy; computed tomography; anus fistula; mucin; human; priority journal; article |
| Journal Title: | Abdominal Radiology |
| Volume: | 44 |
| Issue: | 11 |
| ISSN: | 2366-004X |
| Publisher: | Springer |
| Date Published: | 2019-11-01 |
| Start Page: | 3569 |
| End Page: | 3580 |
| Language: | English |
| DOI: | 10.1007/s00261-019-02019-x |
| PUBMED: | 30993392 |
| PROVIDER: | scopus |
| PMCID: | PMC7357860 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 2 December 2019 -- Source: Scopus |
