Examining mannitol use in kidney cancer surgery: A cautionary tale of extrapolated surgical data Review
| Authors: | Nair, S. M.; Power, N. E.; Coleman, J. A. |
| Review Title: | Examining mannitol use in kidney cancer surgery: A cautionary tale of extrapolated surgical data |
| Abstract: | Mannitol for renal protection during partial nephrectomy is common but unsupported by evidence from clinical trials. The impact of mannitol on renal physiology includes both beneficial and harmful effects. Current understanding of renal ischemia reperfusion injury suggests potentially targetable processes that have a lower potential risk. © 2019 European Association of Urology |
| Keywords: | dose response; drug safety; nonhuman; note; furosemide; acute kidney failure; partial nephrectomy; drug mechanism; kidney function; cold ischemia; kidney injury; kidney ischemia; glomerulus filtration rate; drug metabolism; kidney cancer; mannitol; drug excretion; chronic kidney failure; heart surgery; kidney transplantation; renal protection; acute kidney tubule necrosis; human; kidney preservation; contrast induced nephropathy; renal ischemia reperfusion injury |
| Journal Title: | European Urology Focus |
| Volume: | 5 |
| Issue: | 6 |
| ISSN: | 2405-4569 |
| Publisher: | Elsevier B.V. |
| Date Published: | 2019-11-01 |
| Start Page: | 930 |
| End Page: | 934 |
| Language: | English |
| DOI: | 10.1016/j.euf.2019.09.021 |
| PUBMED: | 31628080 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Note -- Export Date: 2 December 2019 -- Source: Scopus |
