Atypical teratoid/rhabdoid tumor arising from the third cranial nerve Journal Article
| Authors: | Wykoff, C. C.; Lam, B. L.; Brathwaite, C. D.; Biegel, J. A.; McKeown, C. A.; Rosenblum, M. K.; Allewelt, H. B.; Sandberg, D. I. |
| Article Title: | Atypical teratoid/rhabdoid tumor arising from the third cranial nerve |
| Abstract: | An otherwise healthy 6-week-old girl who presented with an isolated left third cranial nerve palsy underwent MRI that revealed an enhancing mass intrinsic to the left third cranial nerve. Rapid enlargement of the lesion over 1 month led to subtotal neurosurgical resection of an atypical teratoid/rhabdoid tumor (AT/RT), a rare, highly aggressive malignancy of infancy closely related histologically to medulloblastoma and primitive neuroectodermal tumor. Despite aggressive chemotherapy, the patient died within 6 months of presentation. This is the first report of an AT/RT presenting as an isolated third cranial nerve palsy caused by tumor arising from within the nerve. © 2008 Lippincott Williams & Wilkins. |
| Keywords: | human tissue; treatment failure; human cell; clinical feature; disease course; case report; cisplatin; cancer combination chemotherapy; pathophysiology; methotrexate; nuclear magnetic resonance imaging; neurosurgery; magnetic resonance imaging; antineoplastic agent; metabolism; multiple cycle treatment; neoplasm recurrence, local; tumor volume; etoposide; antineoplastic combined chemotherapy protocols; tumor markers, biological; cyclophosphamide; vincristine; pathology; tumor marker; cancer mortality; cancer invasion; infant; disease progression; tumor recurrence; teratoma; neoplasm invasiveness; mesencephalon; tumor growth; fatal outcome; carcinomatous meningitis; brain surgery; rhabdoid tumor; eye examination; neurosurgical procedures; cranial nerve tumor; cranial nerve neoplasms; hydrocephalus; fatality; meningeal carcinomatosis; subarachnoid space; oculomotor nerve; ophthalmoplegia; oculomotor nerve disease; oculomotor nerve diseases |
| Journal Title: | Journal of Neuro-Ophthalmology |
| Volume: | 28 |
| Issue: | 3 |
| ISSN: | 1070-8022 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2008-09-01 |
| Start Page: | 207 |
| End Page: | 211 |
| Language: | English |
| DOI: | 10.1097/WNO.0b013e318183c770 |
| PUBMED: | 18769285 |
| PROVIDER: | scopus |
| PMCID: | PMC2839362 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 17 November 2011" - "CODEN: JNEOE" - "Source: Scopus" |
