Task Group 174 report: Utilization of [(18)F]fluorodeoxyglucose positron emission tomography ([(18)F]FDG-PET) in radiation therapy Journal Article


Authors: Das, S. K.; McGurk, R.; Miften, M.; Mutic, S.; Bowsher, J.; Bayouth, J.; Erdi, Y.; Mawlawi, O.; Boellaard, R.; Bowen, S. R.; Xing, L.; Bradley, J.; Schoder, H.; Yin, F. F.; Sullivan, D. C.; Kinahan, P.
Article Title: Task Group 174 report: Utilization of [(18)F]fluorodeoxyglucose positron emission tomography ([(18)F]FDG-PET) in radiation therapy
Abstract: The use of positron emission tomography (PET) in radiation therapy (RT) is rapidly increasing in the areas of staging, segmentation, treatment planning, and response assessment. The most common radiotracer is 18F-fluorodeoxyglucose ([18F]FDG), a glucose analog with demonstrated efficacy in cancer diagnosis and staging. However, diagnosis and RT planning are different endeavors with unique requirements, and very little literature is available for guiding physicists and clinicians in the utilization of [18F]FDG-PET in RT. The two goals of this report are to educate and provide recommendations. The report provides background and education on current PET imaging systems, PET tracers, intensity quantification, and current utilization in RT (staging, segmentation, image registration, treatment planning, and therapy response assessment). Recommendations are provided on acceptance testing, annual and monthly quality assurance, scanning protocols to ensure consistency between interpatient scans and intrapatient longitudinal scans, reporting of patient and scan parameters in literature, requirements for incorporation of [18F]FDG-PET in treatment planning systems, and image registration. The recommendations provided here are minimum requirements and are not meant to cover all aspects of the use of [18F]FDG-PET for RT. © 2019 American Association of Physicists in Medicine
Keywords: treatment response; treatment planning; radiation dose; cancer staging; positron emission tomography; quality control; radiotherapy; radiation response; quality assurance; fdg-pet; fluorodeoxyglucose f 18; radiation therapy; image registration; standardized uptake value; image segmentation; respiratory gated imaging; protocols; human; article; positron emission tomography-computed tomography
Journal Title: Medical Physics
Volume: 46
Issue: 10
ISSN: 0094-2405
Publisher: American Association of Physicists in Medicine  
Date Published: 2019-10-01
Start Page: e706
End Page: e725
Language: English
DOI: 10.1002/mp.13676
PUBMED: 31230358
PROVIDER: scopus
DOI/URL:
Notes: Source: Scopus
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MSK Authors
  1. Heiko Schoder
    311 Schoder
  2. Yusuf E Erdi
    111 Erdi