Significance and management of incidentally diagnosed metastatic papillary thyroid carcinoma in cervical lymph nodes in neck dissection specimens Journal Article
| Authors: | Mandapathil, M.; Lennon, P.; Ganly, I.; Patel, S. G.; Shah, J. P. |
| Article Title: | Significance and management of incidentally diagnosed metastatic papillary thyroid carcinoma in cervical lymph nodes in neck dissection specimens |
| Abstract: | Background: The management of patients with incidentally discovered metastatic thyroid cancer in cervical lymph nodes in neck dissection specimens for other pathologies is unclear. Methods: Retrospective review of neck dissection specimens for nonthyroid malignancy during a 30-year period was undertaken to identify incidental metastatic papillary thyroid cancer (PTC). Results: Twenty-six patients had an incidental finding of PTC in lymph node(s) in neck dissection specimens. Subsequent ultrasound of the thyroid showed nodules in 20 patients. Eleven (42%) underwent total thyroidectomy, 1 (4%) had a lobectomy, and 14 (54%) were kept under active surveillance only. At a median follow-up of 48 months (range 10-189 months), all patients who had undergone surgery and those under surveillance were free of PTC recurrence. Conclusion: Evaluation for detection of a primary thyroid tumor is essential in all patients with incidentally discovered metastatic PTC. Decision regarding surgery or surveillance is dependent on clinical and radiological tumor features and patient factors. © 2019 Wiley Periodicals, Inc. |
| Keywords: | human tissue; aged; primary tumor; major clinical study; neck dissection; advanced cancer; postoperative care; cancer staging; adenocarcinoma; melanoma; cohort analysis; radioactive iodine; recurrent disease; thyroidectomy; oropharynx cancer; salivary gland tumor; cancer epidemiology; incidental finding; thyroid nodule; lobectomy; thyroid papillary carcinoma; mouth cancer; tonsil cancer; papillary thyroid cancer; neck metastases; human; male; female; priority journal; article; occult metastases; cervical lymph node metastasis; aberrant thyroid tissue; nonthyroid primary tumor; salivary adenocarcinoma |
| Journal Title: | Head & Neck |
| Volume: | 41 |
| Issue: | 11 |
| ISSN: | 1043-3074 |
| Publisher: | John Wiley & Sons, Inc. |
| Date Published: | 2019-11-01 |
| Start Page: | 3783 |
| End Page: | 3787 |
| Language: | English |
| DOI: | 10.1002/hed.25905 |
| PUBMED: | 31390117 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 November 2019 -- Source: Scopus |
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