Level v in therapeutic neck dissections for papillary thyroid carcinoma Journal Article


Authors: Khafif, A.; Medina, J. E.; Robbins, K. T.; Silver, C. E.; Weber, R. S.; Rinaldo, A.; Owen, R. P.; Shaha, A. R.; Ferlito, A.
Article Title: Level v in therapeutic neck dissections for papillary thyroid carcinoma
Abstract: Neck dissection for papillary thyroid carcinoma (PTC) is the standard of care for patients with clinical evidence of regional metastases. However, the extent of neck dissection is debatable. The purpose of the current study was to develop evidence-based recommendations for when to include level V, or 1 of its sublevels, among patients with PTC undergoing neck dissection. A literature review of all studies evaluating the occurrence of metastases in level V in patients with regional metastases from PTC undergoing neck dissection was performed. Occurrence of metastases at level V is low in most series (5% to 10%), although a wide range was noticed. In cases in which metastases were found at level V, they occurred almost exclusively at sublevel VB. Sublevel VA was rarely, if ever, involved with metastatic lymph nodes. However, only recently have investigators begun to specify which sublevels of level V are at risk. Therapeutic dissection of level V is indicated when there is clinical evidence of disease involving this zone. Elective dissection of sublevel VB is indicated when there is involvement of level IV, or possibly multiple nodes at levels II and III. Under these circumstances, dissection of sublevel VB is indicated but sublevel VA may be spared. © 2012 Wiley Periodicals, Inc.
Keywords: review; neck dissection; lymph node metastasis; lymph nodes; lymphatic metastasis; morbidity; carcinoma; neoplasm metastasis; thyroidectomy; thyroid carcinoma; thyroid neoplasms; thyroid gland; regional metastasis; differentiated thyroid cancer; papillary thyroid carcinoma; level v; sublevel va; sublevel vb
Journal Title: Head & Neck
Volume: 35
Issue: 4
ISSN: 1043-3074
Publisher: John Wiley & Sons, Inc.  
Date Published: 2013-04-01
Start Page: 605
End Page: 607
Language: English
PROVIDER: scopus
PUBMED: 22287259
DOI: 10.1002/hed.21952
DOI/URL:
Notes: --- - Cited By (since 1996):1 - "Export Date: 1 May 2013" - "CODEN: HEANE" - ":doi 10.1002/hed.21952" - "Source: Scopus"
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  1. Ashok R Shaha
    697 Shaha