MR perfusion and MR spectroscopy of brain neoplasms Review
| Authors: | Gharzeddine, K.; Hatzoglou, V.; Holodny, A. I.; Young, R. J. |
| Review Title: | MR perfusion and MR spectroscopy of brain neoplasms |
| Abstract: | Advances in imaging techniques, such as MR perfusion and spectroscopy, are increasingly indispensable in the management and treatment plans of brain neoplasms: from diagnosing, molecular/genetic typing and grading neoplasms, augmenting biopsy results and improving accuracy, to ultimately directing and monitoring treatment and response. New developments in treatment methods have resulted in new diagnostic challenges for conventional MR imaging, such as pseudoprogression, where MR perfusion has the widest current application. MR spectroscopy is showing increasing promise in noninvasively determining genetic subtypes and, potentially, susceptibility to molecular targeted therapies. © 2019 Elsevier Inc. |
| Keywords: | cancer survival; treatment response; overall survival; review; cancer growth; temozolomide; nuclear magnetic resonance imaging; brain tumor; glioma; brain neoplasms; magnetic resonance imaging; cancer grading; treatment indication; progression free survival; tumor biopsy; diagnostic imaging; brain; contrast enhancement; glioblastoma; clinical evaluation; brain metastasis; magnetic resonance spectroscopy; choline; nuclear magnetic resonance spectroscopy; spectroscopy; inositol; n acetylaspartic acid; radiation necrosis; mr imaging; scintigraphy; lactic acid; perfusion; brain perfusion; procedures; perfusion imaging; cancer prognosis; humans; human; priority journal |
| Journal Title: | Radiologic Clinics of North America |
| Volume: | 57 |
| Issue: | 6 |
| ISSN: | 0033-8389 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2019-11-01 |
| Start Page: | 1177 |
| End Page: | 1188 |
| Language: | English |
| DOI: | 10.1016/j.rcl.2019.07.008 |
| PUBMED: | 31582043 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 November 2019 -- Source: Scopus |
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