Pretreatment evaluation of prostate cancer: Role of MR imaging and 1H MR spectroscopy Journal Article


Authors: Claus, F.; Hricak, H.; Hattery, R. R.
Article Title: Pretreatment evaluation of prostate cancer: Role of MR imaging and 1H MR spectroscopy
Abstract: Magnetic resonance (MR) imaging and hydrogen 1 MR spectroscopy of the prostate gland are performed during the same examination with a conventional clinical MR unit. Prostate zonal anatomy and prostate cancer are best depicted on multiplanar T2-weighted MR images. MR imaging and 1H MR spectroscopy are not used as an initial diagnostic tool. Their use in tumor detection is reserved for patients with elevated prostate-specific antigen levels in whom previous biopsy results were negative. The use of MR imaging and 1H MR spectroscopy for the evaluation of tumor location, local extent (extracapsular extension and/or seminal vesicle invasion), volume, and aggressiveness is generating strong clinical interest. In staging and treatment planning, MR imaging has been shown to have an incremental value additive to the value of clinical nomograms. Furthermore, anatomic and metabolic mapping of the prostate gland with 1H MR spectroscopy offers the possibility of optimizing treatment planning (watchful waiting, surgery, or radiation therapy [intensity-modulated radiation therapy or brachytherapy]), thus further expanding the role of MR imaging in the achievement of patient-specific, individualized treatment. © RSNA, 2004.
Keywords: aged; middle aged; cancer risk; treatment planning; cancer staging; nuclear magnetic resonance imaging; magnetic resonance imaging; cancer diagnosis; neoplasm staging; diagnostic accuracy; adenocarcinoma; prostate specific antigen; tumor localization; tumor volume; diagnostic imaging; prostate cancer; prostatic neoplasms; prostate; prostate biopsy; magnetic resonance spectroscopy; anatomy; proton nuclear magnetic resonance; humans; human; male; article; neoplasms, staging, 844.1214, 844.12145; prostate neoplasms, mr, 844.1214, 844.12145
Journal Title: RadioGraphics
Volume: 24
Issue: Suppl.1
ISSN: 0271-5333
Publisher: Radiological Society of North America, Inc.  
Date Published: 2004-10-01
Start Page: S167
End Page: S180
Language: English
PROVIDER: scopus
PUBMED: 15486239
DOI: 10.1148/24si045516
DOI/URL:
Notes: Radiographics -- Cited By (since 1996):96 -- Export Date: 16 June 2014 -- Source: Scopus
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  1. Filip Claus
    4 Claus
  2. Hedvig Hricak
    419 Hricak