Scleromyxedematous changes in a patient with long-standing mycosis fungoides who progressed to Sézary syndrome Journal Article
| Authors: | Miraflor, A. P.; Pulitzer, M. P.; Myskowski, P. L.; Geller, S. |
| Article Title: | Scleromyxedematous changes in a patient with long-standing mycosis fungoides who progressed to Sézary syndrome |
| Abstract: | Mycosis fungoides (MF) variants with different clinicopathologic and immunohistochemical features have been well-delineated. We report a case of scleromyxedematous changes arising in a patient with long-standing MF who progressed to Sézary syndrome (SS) shortly afterward. Total-skin electron-beam radiation therapy resulted in an excellent response, controlling both the MF/SS and the scleromyxedematous lesions; however, the patient died few months later. Although mucin deposition has been described in association with MF/SS (mainly follicular mucinosis in folliculotropic MF), there are limited reports in the literature on dermal mucinosis and scleromyxedematous changes in MF/SS. The mechanism of this association and its prognostic implications requires further investigation. |
| Journal Title: | American Journal of Dermatopathology |
| Volume: | 41 |
| Issue: | 11 |
| ISSN: | 0193-1091 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2019-11-01 |
| Start Page: | e139 |
| End Page: | e143 |
| Language: | English |
| DOI: | 10.1097/dad.0000000000001464 |
| PUBMED: | 31169525 |
| PROVIDER: | scopus |
| PMCID: | PMC6803053 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 November 2019 -- Source: Scopus |
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