Follow up approaches in thyroid cancer: A risk adapted paradigm Journal Article


Authors: Tuttle, R. M.; Leboeuf, R.
Article Title: Follow up approaches in thyroid cancer: A risk adapted paradigm
Abstract: The primary goal in the follow up of thyroid cancer patients is to identify and treat persistent and recurrent disease at a time that minimizes morbidity and disease specific mortality. This article presents a risk-adapted follow-up paradigm to guide both intensity and methodology of follow-up testing based on initial risk stratification, ongoing risk stratification, and secondary risk stratification that incorporates each of the well-known risk factors for recurrence and death from thyroid cancer, with a response to therapy variable as well as duration of disease-free survival. With a proper understanding of the biology of the disease and with accurate assessments of response to therapy, clinicians are better able to tailor a risk-appropriate follow-up approach to individual patients, minimizing excessive testing while still providing adequate testing to detect clinically significant disease recurrence in a timely fashion. © 2008 Elsevier Inc. All rights reserved.
Keywords: cancer survival; survival analysis; review; cancer recurrence; united states; cancer staging; follow up; follow-up studies; neoplasm recurrence, local; risk factors; health survey; algorithms; risk factor; cancer mortality; radioactive iodine; echography; computer assisted emission tomography; thyroidectomy; thyroid cancer; thyroid neoplasms; thyroglobulin; population surveillance; thyrotropin
Journal Title: Endocrinology and Metabolism Clinics of North America
Volume: 37
Issue: 2
ISSN: 0889-8529
Publisher: Elsevier Inc.  
Date Published: 2008-06-01
Start Page: 419
End Page: 435
Language: English
DOI: 10.1016/j.ecl.2008.02.008
PUBMED: 18502335
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 16" - "Export Date: 17 November 2011" - "CODEN: ECNAE" - "Source: Scopus"
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  1. Robert M Tuttle
    481 Tuttle
  2. Rebecca Leboeuf
    13 Leboeuf