Primary leptomeningeal lymphoma: Report of 9 cases, diagnosis with immunocytochemical analysis, and review of the literature Journal Article


Authors: Lachance, D. H.; O’Neill, B. P.; Macdonald, D. R.; Jaeckle, K. A.; Witzig, T. E.; Li, C. Y.; Posner, J. B.
Article Title: Primary leptomeningeal lymphoma: Report of 9 cases, diagnosis with immunocytochemical analysis, and review of the literature
Abstract: We describe 9 patients who presented with a neoplastic meningitis of lymphomatous origin. No evidence of parenchymal central nervous system or systemic tumor was identified either at the time of presentation or throughout the course of their disease. We have chosen to call this entity “primary leptomeningeal lymphoma” (PLML). This unusual form of neurologic lymphoma must be differentiated from the more common clinical situations of primary parenchymal lymphoma with meningeal involvement and systemic lymphoma complicated by lymphomatous meningitis. © 1991 American Academy of Neurology.
Keywords: immunohistochemistry; adult; clinical article; aged; case report; doxorubicin; conference paper; cytarabine; methotrexate; cyclophosphamide; dexamethasone; vincristine; central nervous system tumor; cerebrospinal fluid; meningeal neoplasms; lymphoma; bleomycin; arachnoid; middle age; human; male; female; priority journal; pia mater
Journal Title: Neurology
Volume: 41
Issue: 1
ISSN: 0028-3878
Publisher: Lippincott Williams & Wilkins  
Date Published: 1991-01-01
Start Page: 95
End Page: 100
Language: English
PUBMED: 1985302
PROVIDER: scopus
DOI: 10.1212/wnl.41.1.95
DOI/URL:
Notes: Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Jerome B Posner
    211 Posner