Vascular soft-tissue sarcomas: An analysis of tumor-related mortality Conference Paper
| Authors: | Karpeh, M. S. Jr; Caldwell, C.; Gaynor, J. J.; Hajdu, S. I.; Brennan, M. F. |
| Title: | Vascular soft-tissue sarcomas: An analysis of tumor-related mortality |
| Conference Title: | 44th Annual Cancer Symposium of the Society of Surgical Oncology |
| Abstract: | Between 1982 and 1990, 69 adult patients were admitted to Memorial Sloan-Kettering Cancer Center with a diagnosis of angiosarcoma, lymphangiosarcoma, or malignant hemangiopericytoma. The existing literature regarding sarcomas focuses on individual histologic conditions or site-specific activity and includes pediatric patients, which makes estimates of survival difficult. We describe the clinical course of all vascular sarcomas, the survival without distant recurrence of patients with vascular sarcomas, and the overall survival of patients with vascular sarcomas. Using Cox's stepwise regression model, histologic characteristics of the tumors, tumor grade, tumor size, and other factors were assessed to determine their prognostic significance. Noncurative treatment and the presence of metastases were the only two factors influencing survival. Tumor grade approached significance. Disease recurrence was common among curatively treated patients (37% of such patients), and more than half of these recurrences involved distant sites. The survival of these patients depends on complete surgical resection and is independent of individual histologic characteristics of the tumor. © 1991, American Medical Association. All rights reserved. |
| Keywords: | adolescent; adult; aged; aged, 80 and over; survival rate; major clinical study; mortality; conference paper; combined modality therapy; neoplasm recurrence, local; angiosarcoma; hemangiosarcoma; sarcoma; neoplasm metastasis; hemangiopericytoma; regression analysis; soft tissue neoplasms; middle age; lymphangioma; vascular surgery; lymphangiosarcoma; prognosis; human; male; female; priority journal; support, u.s. gov't, p.h.s. |
| Journal Title | Archives of Surgery |
| Volume: | 126 |
| Issue: | 12 |
| Conference Dates: | 1991 Mar 26 |
| Conference Location: | Orlando, FL |
| ISBN: | 0004-0010 |
| Publisher: | American Medical Association |
| Date Published: | 1991-12-01 |
| Start Page: | 1474 |
| End Page: | 1481 |
| Language: | English |
| DOI: | 10.1001/archsurg.1991.01410360044008 |
| PUBMED: | 1842176 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Source: Scopus |
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