False-positive findings on 18F-FDG PET/CT: Differentiation of hibernoma and malignant fatty tumor on the basis of fluctuating standardized uptake values Journal Article
| Authors: | Smith, C. S.; Teruya-Feldstein, J.; Caravelli, J. F.; Yeung, H. W. |
| Article Title: | False-positive findings on 18F-FDG PET/CT: Differentiation of hibernoma and malignant fatty tumor on the basis of fluctuating standardized uptake values |
| Abstract: | Objective. Hibernoma is a benign tumor of brown fat that has imaging features similar to those of malignant fat-containing soft-tissue tumors. Hibernoma is metabolically active on 18F-FDG PET/CT, and its presence can lead to false-positive interpretations. We present three cases in which fatty lesions with increased radiotracer uptake identified on FDG PET/CT turned out to be hibernomas. The standardized uptake values of the lesions were similar to those reported in the literature for liposarcoma. However, all three patients had variable standardized uptake values over time. CONCLUSION. Variation in standardized uptake values over time is an imaging characteristic that may be helpful for differentiating hibernoma and malignant fatty tumor. © American Roentgen Ray Society. |
| Keywords: | retrospective studies; case report; cancer staging; positron emission tomography; follow up; laboratory diagnosis; radiopharmaceuticals; computer assisted tomography; diagnosis, differential; differential diagnosis; tomography, x-ray computed; retrospective study; diagnostic agent; fluorodeoxyglucose f 18; computer assisted emission tomography; fluorodeoxyglucose f18; radiopharmaceutical agent; scintiscanning; imaging; radiography; false positive reactions; soft tissue tumor; liposarcoma; pet/ct; tomography, emission-computed; lipoma; hibernoma; neoplasms, adipose tissue |
| Journal Title: | American Journal of Roentgenology |
| Volume: | 190 |
| Issue: | 4 |
| ISSN: | 0361-803X |
| Publisher: | American Roentgen Ray Society |
| Date Published: | 2008-04-01 |
| Start Page: | 1091 |
| End Page: | 1096 |
| Language: | English |
| DOI: | 10.2214/ajr.07.3061 |
| PUBMED: | 18356460 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 10" - "Export Date: 17 November 2011" - "CODEN: AJROA" - "Source: Scopus" |
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