Molecular pathogenesis of head and neck cancers Journal Article
| Author: | Singh, B. |
| Article Title: | Molecular pathogenesis of head and neck cancers |
| Abstract: | Head and neck cancers represent a progressive genetic malady, with genetic aberrations accumulating in response to carcinogen exposure. Although individual genomic aberrations develop at specific time points in the progression axis, the precise role of these abnormalities in tumor progression and cancer behavior remain to be elucidated. This article will give an overview of the current knowledge on the molecular basis for the development of head and neck cancers. © 2008 Wiley-Liss, Inc. |
| Keywords: | cancer survival; clinical trial; review; squamous cell carcinoma; cancer risk; nonhuman; antineoplastic agents; antineoplastic agent; heredity; genetic association; smoking cessation; smoking; receptor, epidermal growth factor; cetuximab; carcinogenesis; panitumumab; chromosome aberration; dna; head and neck cancer; head and neck neoplasms; transcription factor e2f; alcohol; gefitinib; tumor virus infections; virus infection; tumor growth; molecular biology; tobacco; retinol; alcohol consumption; cyclin d1; esophagus cancer; protein p21; retinoic acid; beta carotene; uterine cervix tumor; environmental exposure; alcohol drinking; cyclin dependent kinase 4; wart virus; papillomavirus infections; virus protein; carcinogen; zalutumumab; cyclin dependent kinase 6; wart virus vaccine; papillomavirus vaccines; cyclin dependent kinase inhibitor 2b; cancer pathogenesis; acetaldehyde; traceva; aerosol |
| Journal Title: | Journal of Surgical Oncology |
| Volume: | 97 |
| Issue: | 8 |
| ISSN: | 0022-4790 |
| Publisher: | Wiley Blackwell |
| Date Published: | 2008-06-15 |
| Start Page: | 634 |
| End Page: | 639 |
| Language: | English |
| DOI: | 10.1002/jso.21024 |
| PUBMED: | 18493941 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 7" - "Export Date: 17 November 2011" - "CODEN: JSONA" - "Source: Scopus" |
