Advances in biomaterials and technologies for vascular embolization Review


Authors: Hu, J.; Albadawi, H.; Chong, B. W.; Deipolyi, A. R.; Sheth, R. A.; Khademhosseini, A.; Oklu, R.
Review Title: Advances in biomaterials and technologies for vascular embolization
Abstract: Minimally invasive transcatheter embolization is a common nonsurgical procedure in interventional radiology used for the deliberate occlusion of blood vessels for the treatment of diseased or injured vasculature. A wide variety of embolic agents including metallic coils, calibrated microspheres, and liquids are available for clinical practice. Additionally, advances in biomaterials, such as shape-memory foams, biodegradable polymers, and in situ gelling solutions have led to the development of novel preclinical embolic agents. The aim here is to provide a comprehensive overview of current and emerging technologies in endovascular embolization with respect to devices, materials, mechanisms, and design guidelines. Limitations and challenges in embolic materials are also discussed to promote advancement in the field. © 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Keywords: radiation; radiology; interventional radiology; minimally invasive surgery; minimally invasive; blood vessels; embolization; clinical practices; embolic agents; biodegradable polymers; emerging technologies; catheter-based delivery; vascular embolization; embolic material; transcatheter embolization
Journal Title: Advanced Materials
Volume: 31
Issue: 33
ISSN: 0935-9648
Publisher: Wiley V C H Verlag Gmbh  
Date Published: 2019-08-16
Start Page: 1901071
Language: English
DOI: 10.1002/adma.201901071
PROVIDER: scopus
PUBMED: 31168915
PMCID: PMC7014563
DOI/URL:
Notes: Review -- Export Date: 30 August 2019 -- Source: Scopus
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