Small cell carcinoma of the esophagus: Cytology and immunohistology in four cases Journal Article
| Authors: | Hoda, S. A.; Hajdu, S. I. |
| Article Title: | Small cell carcinoma of the esophagus: Cytology and immunohistology in four cases |
| Abstract: | Four cases of small cell carcinoma of the esophagus diagnosed by cytology, with subsequent histologic confirmation, were reviewed. The presence of small malignant cells in isolation with minimal cytoplasm was the common characteristic cytologic finding. Cellular molding was observed only focally in two cases, and streaking of nuclear material was not observed in any smear. The tumor cells were argyrophilic and not argentaffinic. Immunohistochemically the neoplastic cells were consistently immunoreactive with low-molecular-weight cytokeratins and epithelial membrane antigen. Esophageal washings as well as endoscopic biopsies yielded diagnostic material in all cases, but the histologic material was remarkable for crush artifacts that hindered the microscopic interpretation. |
| Keywords: | human tissue; aged; human cell; review; cell nucleus membrane; cytology; immunoreactivity; immunoenzyme techniques; cancer cytodiagnosis; chromatin; tumor cell; cytoplasm; cytokeratin; endoscopic biopsy; esophagus carcinoma; esophageal neoplasms; small cell carcinoma; epithelial membrane antigen; carcinoma, small cell; middle age; papanicolaou test; immunohistology; human; male; priority journal; argyrophilia |
| Journal Title: | Acta Cytologica |
| Volume: | 36 |
| Issue: | 2 |
| ISSN: | 0001-5547 |
| Publisher: | S. Karger AG |
| Date Published: | 1992-03-01 |
| Start Page: | 113 |
| End Page: | 120 |
| Language: | English |
| PUBMED: | 1311883 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Source: Scopus |
