The role of bone marrow-derived cells in tumor angiogenesis and metastatic progression Journal Article


Authors: Papaspyridonos, M.; Lyden, D.
Article Title: The role of bone marrow-derived cells in tumor angiogenesis and metastatic progression
Abstract: Tumor angiogenesis is orchestrated by a complex set of secreted factors and collaboration between many different cell types. This chapter discusses the role of tumor-secreted angiogenic factors that are responsible for the recruitment of bone marrow-derived cells (BMDCs) at tumor sites and their role in tumor angiogenesis and progression. © 2008 Elsevier Inc. All rights reserved.
Keywords: signal transduction; review; nonhuman; receptors, vascular endothelial growth factor; neoplasms; animals; bone marrow cells; tumor localization; metastasis; cell differentiation; angiogenesis; neovascularization, pathologic; endothelium cell; disease progression; neoplasm metastasis; fibroblast; cell movement; bone marrow cell; hematopoietic stem cell; tumor growth; stroma cell; cell motility; vasculotropin receptor 1; stromal cell derived factor 1; chemokine cxcl12; receptors, cxcr4; chemokine receptor cxcr4
Journal Title: Methods in Enzymology
Volume: 444
ISSN: 0076-6879
Publisher: Academic Press  
Date Published: 2008-01-01
Start Page: 255
End Page: 269
Language: English
DOI: 10.1016/s0076-6879(08)02811-5
PUBMED: 19007668
PROVIDER: scopus
DOI/URL:
Notes: Chapter 11 in: "Angiogenesis: In Vivo Systems, Part A" (ISBN: 978-0-12-374313-8) --- - "Cited By (since 1996): 4" - "Export Date: 17 November 2011" - "CODEN: MENZA" - "Source: Scopus"
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  1. David C Lyden
    87 Lyden