Authors: | Papaspyridonos, M.; Lyden, D. |
Article Title: | The role of bone marrow-derived cells in tumor angiogenesis and metastatic progression |
Abstract: | Tumor angiogenesis is orchestrated by a complex set of secreted factors and collaboration between many different cell types. This chapter discusses the role of tumor-secreted angiogenic factors that are responsible for the recruitment of bone marrow-derived cells (BMDCs) at tumor sites and their role in tumor angiogenesis and progression. © 2008 Elsevier Inc. All rights reserved. |
Keywords: | signal transduction; review; nonhuman; receptors, vascular endothelial growth factor; neoplasms; animals; bone marrow cells; tumor localization; metastasis; cell differentiation; angiogenesis; neovascularization, pathologic; endothelium cell; disease progression; neoplasm metastasis; fibroblast; cell movement; bone marrow cell; hematopoietic stem cell; tumor growth; stroma cell; cell motility; vasculotropin receptor 1; stromal cell derived factor 1; chemokine cxcl12; receptors, cxcr4; chemokine receptor cxcr4 |
Journal Title: | Methods in Enzymology |
Volume: | 444 |
ISSN: | 0076-6879 |
Publisher: | Academic Press |
Date Published: | 2008-01-01 |
Start Page: | 255 |
End Page: | 269 |
Language: | English |
DOI: | 10.1016/s0076-6879(08)02811-5 |
PUBMED: | 19007668 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Chapter 11 in: "Angiogenesis: In Vivo Systems, Part A" (ISBN: 978-0-12-374313-8) --- - "Cited By (since 1996): 4" - "Export Date: 17 November 2011" - "CODEN: MENZA" - "Source: Scopus" |