A physiological function for ferroptosis in tumor suppression by the immune system Journal Article
| Authors: | Stockwell, B. R.; Jiang, X. |
| Article Title: | A physiological function for ferroptosis in tumor suppression by the immune system |
| Abstract: | Ferroptosis is a form of regulated cell death involving lethal peroxidation of phospholipids (Hirschhorn and Stockwell, 2019). Recent results reveal that ferroptosis mediates the tumor suppressive activity of interferon gamma secreted by CD8+ T cells in response to immune checkpoint blockade, suggesting the immune system may function in part through ferroptosis to prevent tumorigenesis (Wang et al., 2019). © 2019 Elsevier Inc. |
| Journal Title: | Cell Metabolism |
| Volume: | 30 |
| Issue: | 1 |
| ISSN: | 1550-4131 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2019-07-02 |
| Start Page: | 14 |
| End Page: | 15 |
| Language: | English |
| DOI: | 10.1016/j.cmet.2019.06.012 |
| PUBMED: | 31269423 |
| PROVIDER: | scopus |
| PMCID: | PMC6944065 |
| DOI/URL: | |
| Notes: | Short Survey -- Source: Scopus |
