Surgical management patterns of sinonasal malignancy: A population-based study Journal Article

   


Authors: Husain, Q.; Joshi, R. R.; Cracchiolo, J. R.; Roman, B. R.; Ganly, I.; Tabar, V.; Cohen, M. A.
Article Title: Surgical management patterns of sinonasal malignancy: A population-based study
Abstract: Objectives ?Determining surgical trends and outcomes for sinonasal tumors is challenging given their low incidence and heterogeneous pathology. This study utilized the National Cancer Database (NCDB) to identify trends and outcomes associated with surgical management of sinonasal tumors. Design ?Retrospective database analysis. Setting ?National Cancer Database. Participants ?Patients with sinonasal malignancies identified from the NCDB between 2010 and 2015. Main Outcome Measures ?The primary outcome was the choice of surgical therapy used for sinonasal tumor resection: endoscopic versus open approach. Each was cohort analyzed with respect to various demographic and clinicopathologic factors. A treatment effect model was used to identify potential differences between surgical approaches. Survival was evaluated using Kaplan-Meier analysis. Results ?A total of 10,193 patients with sinonasal malignancies were identified in the NCDB database; of these, 2,292 had a documented subsite, histology, and definitive surgical treatment with documented surgical approach and were included in the analysis. About 71.9% of patients had an open approach and 28.1% a purely endoscopic procedures. Tumor histology, treatment facility type, margin status, and length of stay were all variables that were associated with significant differences between the open and endoscopic cohort. Five-year survival rates for the open and endoscopic cohorts were not significantly different (59.6 and 60.8%, respectively). Conclusions ?Assessment of the NCDB revealed that 28% patients with sinonasal malignancy were selected for endoscopic surgery. These patients had comparable oncologic outcomes to open resection. © 2019 Georg Thieme Verlag KG Stuttgart · New York.
Keywords: adult; cancer survival; controlled study; human tissue; cancer surgery; major clinical study; histopathology; surgical approach; retrospective study; histology; length of stay; endoscopic surgery; surgery; kaplan meier method; endoscopy; population-based; potential difference; human; male; female; article; ncdb; sinonasal malignancies; sinonasal tumor
Journal Title: Journal of Neurological Surgery. Part B: Skull Base
Volume: 80
Issue: 4
ISSN: 2193-6331
Publisher: Thieme Publishing  
Date Published: 2019-08-01
Start Page: 371
End Page: 379
Language: English
DOI: 10.1055/s-0038-1675233
PROVIDER: scopus
PMCID: PMC6635118
PUBMED: 31316883
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069199462&doi=10.1055%2fs-0038-1675233&partnerID=40&md5=3943022c0beda177967c206831df6908
Notes: Article -- Export Date: 2 August 2019 -- Source: Scopus
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MSK Authors
  1. Viviane S Tabar
    224 Tabar
  2. Ian Ganly
    430 Ganly
  3. Benjamin Raphael Roman
    75 Roman
  4. Jennifer Rose Cracchiolo
    98 Cracchiolo
  5. Marc A Cohen
    130 Cohen
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