Genetics of transitional cell carcinoma Journal Article
| Authors: | Klein, E. A.; Chaganti, R. S. K. |
| Article Title: | Genetics of transitional cell carcinoma |
| Abstract: | Several models of genetic events which define the origin and progression of human tumors have been elucidated over the last several years. These models suggest that the study of tumors at the level of both the chromosome and the gene can be useful in elucidating molecular events in tumor progression and in determining the biologic behavior of individual tumors. The genetics of transitional cell carcinomas are reviewed with emphasis on potential mechanisms of tumorigenicity and the clinical utility of genetic markers. Copyright © 1992 Wiley‐Liss, Inc., A Wiley Company |
| Keywords: | human cell; genetics; mutation; review; chromosome; neoplasm recurrence, local; gene amplification; retinoblastoma; chronic myeloid leukemia; cancer genetics; chromosome aberration; oncogene; tumor suppressor gene; tumor recurrence; cancer cell; carcinogenicity; predictive value of tests; models, genetic; dna sequence; bladder neoplasms; chromosome aberrations; tumor growth; carcinoma, transitional cell; chromosome deletion; karyotyping; transitional cell carcinoma; chromosomes; genetic markers; philadelphia 1 chromosome; monosomy; dna hybridization; chromosome banding pattern; chromosome disorders; human; karyotypes |
| Journal Title: | Seminars in Surgical Oncology |
| Volume: | 8 |
| Issue: | 5 |
| ISSN: | 8756-0437 |
| Publisher: | John Wiley & Sons |
| Date Published: | 1992-09-01 |
| Start Page: | 260 |
| End Page: | 266 |
| Language: | English |
| DOI: | 10.1002/ssu.2980080503 |
| PUBMED: | 1462095 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Source: Scopus |
