Pretransfusion blood irradiation: Clinical rationale and dosimetric considerations Journal Article
| Authors: | Masterson, M. E.; Febo, R. |
| Article Title: | Pretransfusion blood irradiation: Clinical rationale and dosimetric considerations |
| Abstract: | The irradiation of blood before transfusion into immunosuppressed patients is an increasingly common technique used to prevent graft-versus-host disease. A technical procedure is described for the calibration of blood irradiators, including the determination of absolute dose rate and relative dose distribution over the blood volume. Results of dose rate measurements on commercially available irradiators indicate differences of + 5% to — 13% with manufacturer-supplied calibrations and variations in the relative dose rate over the irradiation volume from 70% to 180%. The clinical implications of these findings and the need for accurate dosimetry are discussed. © 1992, American Association of Physicists in Medicine. All rights reserved. |
| Keywords: | radiation dose; quality control; calibration; risk factor; radiation dosage; models, theoretical; blood; dosimetry; quality assurance; irradiation; blood transfusion; graft versus host reaction; acquired immunodeficiency syndrome; immune deficiency; graft vs host disease; blood volume; immunologic deficiency syndromes; hiv infections; nuclear physics; immunosuppression; human; priority journal; article; x ray dose distribution; blood irradiation |
| Journal Title: | Medical Physics |
| Volume: | 19 |
| Issue: | 3 |
| ISSN: | 0094-2405 |
| Publisher: | American Association of Physicists in Medicine |
| Date Published: | 1992-05-01 |
| Start Page: | 649 |
| End Page: | 657 |
| Language: | English |
| DOI: | 10.1118/1.596809 |
| PUBMED: | 1508104 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Source: Scopus |
