Adjuvant therapy in rectal cancer Journal Article
| Author: | Cohen, A. M. |
| Article Title: | Adjuvant therapy in rectal cancer |
| Abstract: | Local failure in the pelvis following radical surgery for rectal cancer produces severe morbidity and responds poorly to subsequent therapy. Overall, 25 % of rectal cancer patients will recur in the pelvis. The use of adjuvant pelvic radiation therapy combined with systemic chemotherapy is effective in reducing the incidence of local recurrence as well as subsequent distant metastases. Current clinical trials are evaluating various radiation-chemotherapy-surgical interactions as well as the most efficacious chemotherapy program. |
| Keywords: | cancer chemotherapy; cancer surgery; fluorouracil; cancer combination chemotherapy; multimodality cancer therapy; antineoplastic agents; cancer adjuvant therapy; cancer radiotherapy; postoperative care; chemotherapy, adjuvant; combined modality therapy; treatment; antineoplastic combined chemotherapy protocols; radiotherapy dosage; vincristine; folinic acid; preoperative treatment; rectal neoplasms; rectum cancer; intravenous drug administration; rectum; oral drug administration; semustine; cancer; human; priority journal; article |
| Journal Title: | Hepato-Gastroenterology |
| Volume: | 39 |
| Issue: | 3 |
| ISSN: | 0172-6390 |
| Publisher: | H.G.E. Update Medical Publishing Ltd. |
| Date Published: | 1992-06-01 |
| Start Page: | 215 |
| End Page: | 221 |
| Language: | English |
| PUBMED: | 1505892 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 30 July 2019 -- Source: Scopus |
