Immunogenetics of cell surface antigens of human cancer Journal Article
| Author: | Rettig, W. J. |
| Article Title: | Immunogenetics of cell surface antigens of human cancer |
| Abstract: | Hybridoma technology, immunohistochemistry and molecular genetic techniques have paved the way for a general serological mapping of molecules expressed on the surface of normal and neoplastic cells. The emerging findings challenge cell lineage-based models of differentiation and point to new, modular concepts to explain complex tumor phenotypes. In parallel studies, the repertoire of T-cell recognized tumor antigens - still mysterious but probably quite distinct from the antibody-defined repertoire - has also become accessible to molecular analysis. © 1992. |
| Keywords: | immunohistochemistry; review; molecular genetics; glioma; neoplasms; t lymphocyte; t-lymphocytes; phenotype; melanoma; metastasis; ovary cancer; epidermal growth factor receptor; protein; immunoglobulin; cell differentiation; peptide; cml; chronic myeloid leukemia; tumor antigen; stem cell; monoclonal antibody; ewing sarcoma; extracellular matrix; membrane antigen; antigens, neoplasm; antigen recognition; ctl; cytotoxic t lymphocyte; neoplasm metastasis; growth regulation; hybridoma; egfr; hermes antigen; major histocompatibility complex; serology; antigens, surface; chronic myelogenous leukemia; mucin; mhc; tcr; mab; ewing's sarcoma; neu differentiation factor; ncam; neural cell adhesion molecule; receptors, lymphocyte homing; immunogenetics; folate binding protein; ig; es; rough endoplasmic reticulum; cancer; human; ecm; t-cell receptor; breakpoint cluster region; bcr; interleukin-2 receptor; folate-binding protein; fbf; il-2r; ndf; rer |
| Journal Title: | Current Opinion in Immunology |
| Volume: | 4 |
| Issue: | 5 |
| ISSN: | 0952-7915 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1992-01-01 |
| Start Page: | 630 |
| End Page: | 640 |
| Language: | English |
| DOI: | 10.1016/0952-7915(92)90039-h |
| PUBMED: | 1418731 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 30 July 2019 -- Source: Scopus |
