Utility of brain FDG-PET in primary CNS lymphoma Journal Article
| Authors: | Mohile, N. A.; Deangelis, L. M.; Abrey, L. E. |
| Article Title: | Utility of brain FDG-PET in primary CNS lymphoma |
| Abstract: | 18Fluoro-deoxyglucose positron emission tomography (FDG-PET) imaging has been widely incorporated into the management of systemic non-Hodgkin lymphoma. However, its utility in primary central nervous system lymphoma (PCNSL) is unclear. We report 28 PCNSL patients who underwent brain FDG-PET to inform clinical management. Baseline PET imaging demonstrated hypermetabolism consistent with aggressive lymphoma in 75% (9/12) of patients. FDG-PET used for response assessment or the interpretation of nonspecific magnetic resonance imaging abnormalities showed hypermetabolism in 50% (10/20) of patients, which was important in guiding further management. This data suggests that FDG-PET imaging in PCNSL is useful and may have a role in response assessment. |
| Keywords: | adult; aged; aged, 80 and over; middle aged; positron emission tomography; brain tumor; methodology; brain neoplasms; radiopharmaceuticals; pathology; validation study; diagnostic agent; brain; lymphoma; fluorodeoxyglucose f 18; fluorodeoxyglucose f18; positron-emission tomography; radiopharmaceutical agent; scintiscanning |
| Journal Title: | Clinical Advances in Hematology & Oncology |
| Volume: | 6 |
| Issue: | 11 |
| ISSN: | 1543-0790 |
| Publisher: | Millennium Medical Publishing, Inc |
| Date Published: | 2008-11-01 |
| Start Page: | 818 |
| End Page: | 820, 840 |
| Language: | English |
| PUBMED: | 19194366 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 5" - "Export Date: 17 November 2011" - "Source: Scopus" |
