Pseudomyxoma peritonei of appendiceal origin: The Memorial Sloan‐Kettering Cancer Center experience Journal Article


Authors: Smith, J. W.; Kemeny, N.; Caldwell, C.; Banner, P.; Sigurdson, E.; Huvos, A.
Article Title: Pseudomyxoma peritonei of appendiceal origin: The Memorial Sloan‐Kettering Cancer Center experience
Abstract: Background. Pseudomyxoma peritonei is a rare clinical entity in which the peritoneal surfaces and omentum are involved with diffuse gelatinous mucinous implants. It originates from ruptured mucinous tumors of the appendix or ovary. Methods. The authors examined the experience with 34 patients with pseudomyxoma peritonei seen at Memorial Sloan‐Kettering Cancer Center from 1952–1989. Of these, 17 cases were identified to be of appendiceal origin. Results. All patients underwent celiotomy and cy to‐reduction. The median survival time from diagnosis was 75 months. It was found that long‐term survival can be achieved by operation alone. When conditions do recur, chemotherapy may be valuable. Conclusions. Pseudomyxoma peritonei of appendiceal origin is a rare low‐grade malignancy. Initial treatment consists of cytoreduction in an attempt to render the patient locally disease‐free. Long‐term survival can be obtained by operation alone, even if gross disease is present at the end of the procedure. Systemic chemotherapy should be reserved for patients with proven recurrence. Cancer 1992; 70396–401. Copyright © 1992 American Cancer Society
Keywords: adult; cancer chemotherapy; cancer survival; clinical article; aged; cancer surgery; survival rate; clinical feature; cancer recurrence; postoperative period; combined modality therapy; chemotherapy; preoperative evaluation; computer assisted tomography; antineoplastic combined chemotherapy protocols; adenocarcinoma, mucinous; cancer mortality; appendix; cytoreduction; computed tomography; mucinous carcinoma; pseudomyxoma peritonei; peritoneum pseudomyxoma; appendiceal neoplasms; middle age; omentum; human; male; female; priority journal; article; mucinous tumor
Journal Title: Cancer
Volume: 70
Issue: 2
ISSN: 0008-543X
Publisher: Wiley Blackwell  
Date Published: 1992-07-15
Start Page: 396
End Page: 401
Language: English
DOI: 10.1002/1097-0142(19920715)70:2<396::Aid-cncr2820700205>3.0.Co;2-a
PUBMED: 1319813
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 30 July 2019 -- Source: Scopus
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  1. Nancy Kemeny
    543 Kemeny
  2. Andrew G Huvos
    289 Huvos