Carcinosarcoma of the submandibular salivary gland: Immunohistochemical findings Journal Article

  


Authors: Bleiweiss, I. J.; Huvos, A. G.; Lara, J.; Strong, E. W.
Article Title: Carcinosarcoma of the submandibular salivary gland: Immunohistochemical findings
Abstract: Carcinosarcomas of the salivary glands are rare lesions that generally have been associated with benign mixed tumors. The authors report a case of a submandibular gland lesion, which occurred in a 64‐year‐old man, that was composed of intermingled ductal type adenocarcinoma and osteogenic sarcoma with a large component of osteoclast‐like giant cells. The local recurrence of the tumor was entirely sarcomatous with no epithelial component observed. There was no histologic evidence of a preexisting or coexisting pleomorphic adenoma. Immunohistochemical studies confirmed two separate populations of tumor cells, corresponding to the histologic growth pattern. The authors review the literature and discuss histogenetic implications of distinction between de novo carcinosarcoma and carcinosarcoma in association with pleomorphic adenoma. Copyright © 1992 American Cancer Society
Keywords: immunohistochemistry; osteosarcoma; adult; human tissue; case report; neck dissection; cancer incidence; adenocarcinoma; glial fibrillary acidic protein; immunoenzyme techniques; tumor recurrence; tumor cell line; malignant neoplastic disease; protein s 100; myoepithelium cell; cytokeratin; carcinoma, intraductal, noninfiltrating; epithelial membrane antigen; mandible resection; vimentin; carcinosarcoma; middle age; giant cell tumor; pleomorphic adenoma; submandibular gland; human; male; priority journal; article; submandibular gland neoplasms
Journal Title: Cancer
Volume: 69
Issue: 8
ISSN: 0008-543X
Publisher: Wiley Blackwell  
Date Published: 1992-04-15
Start Page: 2031
End Page: 2035
Language: English
DOI: 10.1002/1097-0142(19920415)69:8<2031::Aid-cncr2820690804>3.0.Co;2-3
PUBMED: 1311976
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026551622&doi=10.1002%2f1097-0142%2819920415%2969%3a8%3c2031%3a%3aAID-CNCR2820690804%3e3.0.CO%3b2-3&partnerID=40&md5=45ce201bf26e9ba99ba967ec9596bf7d
Notes: Article -- Export Date: 30 July 2019 -- Source: Scopus
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MSK Authors
  1. Andrew G Huvos
    289 Huvos
  2. Elliot W Strong
    97 Strong
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