Management of small soft-tissue sarcoma of the extremity in adults Conference Paper
| Authors: | Geer, R. J.; Woodruff, J.; Casper, E. S.; Brennan, M. F. |
| Title: | Management of small soft-tissue sarcoma of the extremity in adults |
| Conference Title: | 45th Annual Cancer Symposium of the Society of Surgical Oncology |
| Abstract: | To determine the significance of small (≤5 cm in diameter) soft-tissue sarcoma of the extremity, 174 adult patients were identified from information that had been entered prospectively into a database of 1742 patients between July 1982 and December 1990. Median follow-up was 48 months. The majority of tumors were high grade (n=114; 66%). Local recurrence (n=17) was seen in patients with both high-grade (11 %) and low-grade tumors (7%). Distant metastases were seen in 7% of high-grade tumors and in no low-grade tumors. The overall 5-year survival rate was 94% for all patients. Grade, depth, location, type of operation, and sex did not affect 5-year survival or local recurrence-free survival. Neither postoperative adjuvant chemotherapy nor radiation therapy resulted in superior 5-year survival or local recurrence-free survival when compared with no postoperative treatment. The prognosis of these lesions is favorable, and no additional prognostic factors were identified. Inclusion of these patients into adjuvant therapy trials examining survival is inappropriate. © 1992, American Medical Association. All rights reserved. |
| Keywords: | adolescent; adult; cancer survival; aged; aged, 80 and over; cancer surgery; survival rate; major clinical study; cancer localization; cancer recurrence; multimodality cancer therapy; conference paper; cancer radiotherapy; chemotherapy, adjuvant; combined modality therapy; cancer staging; follow up; follow-up studies; neoplasm staging; cancer grading; prospective studies; metastasis; neoplasm recurrence, local; radiotherapy; risk factors; data base; sarcoma; limb; adjuvant chemotherapy; amputation; limb tumor; soft tissue sarcoma; extremities; cancer care facilities; new york city; soft tissue neoplasms; middle age; prognosis; human; male; female; priority journal; support, u.s. gov't, p.h.s. |
| Journal Title | Archives of Surgery |
| Volume: | 127 |
| Issue: | 11 |
| Conference Dates: | 1992 Mar 16-17 |
| Conference Location: | New York, NY |
| ISBN: | 0004-0010 |
| Publisher: | American Medical Association |
| Date Published: | 1992-11-01 |
| Start Page: | 1285 |
| End Page: | 1289 |
| Language: | English |
| DOI: | 10.1001/archsurg.1992.01420110027007 |
| PUBMED: | 1444788 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 30 July 2019 -- Source: Scopus |
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