Characteristics of cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome Conference Paper


Author: Heinemann, M. H.
Title: Characteristics of cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome
Conference Title: Clinical Implications of Herpesvirus Infections in Patients with AIDS
Abstract: Cytomegalovirus (CMV) retinitis is the most common ocular opportunistic infection in patients with acquired immunodeficiency syndrome (AIDS). The disease is inexorably progressive when untreated, making early detection and prompt treatment essential for preservation of functional vision. The retinitis tends to be unilateral at presentation but often becomes bilateral as it progresses. Lesions may be unifocal or multifocal and may appear in the posterior retina or peripheral retina. Primary ophthalmoscopic features of CMV retinitis include white granular zones of retinal necrosis, variable degrees of associated hemorrhage, and low-grade iritis and vitritis. Differential diagnosis is aided by characteristic features of CMV retinitis and other AIDS-related retinopathies. Initial treatment with ganciclovir or foscarnet has been found to stabilize retinitis, and maintenance therapy with either has been shown to prolong the time to retinitis progression. Further studies should help to determine the optimal approach to treatment of the disease. © 1992.
Keywords: clinical feature; neutropenia; conference paper; nephrotoxicity; blood toxicity; pathology; history; retina; acquired immune deficiency syndrome; acquired immunodeficiency syndrome; foscarnet; ganciclovir; cytomegalovirus; zidovudine; antiviral agents; phosphonoacetic acid; retinitis; cytomegalovirus infections; human; priority journal; eye infections, viral
Journal Title The American Journal of Medicine
Volume: 92
Issue: 2 SUPPL. 1
Conference Dates: 1991 Apr 6
Conference Location: New York, NY
ISBN: 0002-9343
Publisher: Elsevier Inc.  
Date Published: 1992-02-14
Start Page: S12
End Page: S16
Language: English
DOI: 10.1016/0002-9343(92)90331-5
PUBMED: 1310570
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 30 July 2019 -- Source: Scopus
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