Giant cell tumor of the spine Journal Article
| Authors: | Luther, N.; Bilsky, M. H.; Härtl, R. |
| Article Title: | Giant cell tumor of the spine |
| Abstract: | Giant cell tumors are benign but locally aggressive neoplasms that typically affect the extremities. When involving the spine, the tumors occur predominantly in the sacrum. Gross total resection of the tumor with wide margins yields good results in terms of survival. However, it carries a significant potential for morbidity and disability. Subtotal resection with adjuvant radiation carries a risk for recurrence or, more concerning, sarcomatous malignant transformation. Endovascular tumor embolizations have also been attempted to control unresectable tumors, and have been performed with moderate degrees of success. Outcomes are analyzed outcomes following surgery, radiation therapy, and tumor embolization. © 2008 Elsevier Inc. All rights reserved. |
| Keywords: | treatment outcome; surgical technique; survival rate; review; artificial embolism; pathophysiology; adjuvant therapy; outcome assessment; recurrence risk; tumor localization; neoplasm recurrence, local; radiotherapy; morbidity; diagnostic imaging; spinal cord compression; spine; spinal neoplasms; benign tumor; malignant transformation; embolization, therapeutic; sacrum; disability; neurosurgical procedures; spine tumor; giant cell tumor; giant cell tumor of bone |
| Journal Title: | Neurosurgery Clinics of North America |
| Volume: | 19 |
| Issue: | 1 |
| ISSN: | 1042-3680 |
| Publisher: | W.B. Saunders Co-Elsevier Inc. |
| Date Published: | 2008-01-01 |
| Start Page: | 49 |
| End Page: | 55 |
| Language: | English |
| DOI: | 10.1016/j.nec.2007.09.009 |
| PUBMED: | 18156047 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 8" - "Export Date: 17 November 2011" - "CODEN: NCNAF" - "Source: Scopus" |
